1. AIKEN, Tecnología Ocular Preventiva, SL, Valencia, Spain
2. Hospital Universitario y tecnológico La Fe, Valencia, Spain
3. Departamento de Óptica, Universidad de Valencia, Spain
4. Centro de Tecnologías Físicas, Universidad Politécnica de Valencia, Spain
5. Universidad CEU, Valencia, Spain
Around 40 years of age begins a new visual situation, presbyopia. Almost always the patient perceives it as something very negative. It does not matter whether or not he was wearing glasses before. The feeling of losing the possibility of close focus is something that makes daily life very difficult. In addition, the implementation of the problem is rapid and, either, it is the first sign of that “aging” sensation, or it is associated with other symptoms that will remind us that time passes inexorably reducing our aptitudes little by little. The first correction method to solve or alleviate the problem is the glasses, either for near or progressive, but this does nothing but ratify that sense of aging that we all try to avoid, so we will quickly look for any other solution that avoids that functional and aesthetic dependence of the spectacles. Perhaps one of the first methods of correcting presbyopia, seeking this independence of the glasses, becomes the use of contact lenses, but is this really a solution? Let us study it more closely.
Leonardo Da Vinci, Descartes, are illustrious names that were already directly associated with contact lenses, and almost from the beginning, talking about contact lenses is closely associated with talking about the materials that compose them.
Currently the materials are very diverse, but we can still divide them into "soft" or "hard" lenses. In both cases, the polymers obtained have improved oxygen permeability, wetting and therefore tolerance recently up to unsuspected levels. Rigid gas permeable (RGP) lenses and silicone hydrogel lenses are usually tolerated much better than other options.
When it comes to correct presbyopia using contact lenses, all these materials, or combinations of them as piggy-back, can be proposed, although the proportion of users of soft lenses of daily or monthly use has clearly increased in recent years.
In general, in this type of patients, we must bear in mind that presbyopia is directly related to age and therefore to hormonal changes, hydration, alterations of the ocular surface... Thus, if we talk about soft contact lenses we have to look for high hydration materials, such as silicone hydrogels, aiming for an increase in comfort and discard other materials due to their clear intolerance in these patients.
There are several ways to achieve improved vision. We will be developing each of these treatment strategies that we can summarize as:
● Monovision
● Simultaneous vision lenses
In general, we can say that this strategy seeks to leave one eye for far vision and another for near vision, the non-dominant eye being the one used for close. Although a priori it seems strange, it is one of the most accepted strategies and is considered to have a 70% acceptance. However, the most important key point in this strategy is to choose the patient very well.
When choosing the patient it will be more accepted in low ametropia than in patients with a similarity between the graduation of both eyes, they must be motivated patients and it is better if they were already contact lens wearers since if they were not there are many variables that we are going to introduce in the patient (lens size, different vision with one eye and another...).
It is obvious that by using this technique, while gaining in width of visual field and vision, we are going to have a loss in binocular vision, so we should rule out those patients who have small binocular vision problems.
There will be different approaches, which can be summarized in the following:
● Pure monovision
● Mini-monovision
● Modified monovision
● Mix & match
We need to create an important dioptric difference between both eyes. We will always leave the dominant eye totally corrected for far, and in the other eye we will leave a myopia of around 2.5 diopters. We must ensure in the clinic that the patient tolerates this well, that it does not generate spatial vision problems that do not allow him to perform his daily tasks. Thus, we could even do the adaptation in two or three stages, so that the user can adapt in a stepped-like fashion to the new situation. The adaptation will be better in patients in whom there was previously a large difference between the graduation of both eyes. In addition, it will be more tolerated in myopic than in hyperopic patients, and it is difficult for those with significant astigmatism to be a good treatment option.
This is the same strategy as the previous one, but with less difference between both eyes. In general, a difference of 1.5 diopters is tolerated very well, and if instead of leaving the eye completely emmetrope, we sacrifice some of the far vision, leaving it slightly myopic, we can increase the depth of field, leaving a very good useful vision with a great tolerance.
In this case we have two alternatives. In the first one (Modified monovision), we place a monofocal lens for distance in the dominant eye, and a multifocal contact lens in the other eye. This could be done in patients who have not tolerated mini-monovision because they require greater visual acuity for far. It is less tolerated than the previous one, but it can be proposed in hyperopic patients, perhaps with better acceptance. In the second one (Mix & Match), both eyes are going to be corrected with a multifocal lens, but each one with a different design. In the dominant eye we place a contact lens with a central part to correct far vision and a peripheral part for near vision, while in the non-dominant eye we will do the inverse, the central part will be for near and the peripheral for far (see Figure 1). If we decide to use this strategy, it is very important to try it first in the consultation and even warn of a period of adaptation of weeks until getting an adequate vision with a certain naturalness in the day to day life.
Figure 1: Typical multifocal contact lens designs used in the Mix & Match technique.
Unlike the monovision technique and its variants, in simultaneous vision both eyes carry the same lens design, which can be bifocal, multifocal or aspheric of extended focus. These in turn can have several designs. We may mention:
● Concentric
● Segmented
Concentric contact lenses may have two or more annular zones with alternating far-close powers (see Figure 2).
The segmented ones are bifocals that present a vertical difference, being in general the upper part of it for correction of far and the lower has the addition for close. Like lenses for astigmatism correction, in these lenses it is very important that they maintain their position, so they are constructed with a ballast prism that allows a stable position in the eye against blinking.
Aspherical lenses do not have annular zones, but a gradual transition of power between that corresponding to the far and near compensation (or vice versa) as we move away from the center of the lens (see Figure 2c). These designs are also the ones used in the Mix & Match technique mentioned above. Concentric designs give better results in young presbytes with low additions.
Figure 2. Multifocal lens designs. a) Concentric. b) Segmented. c) Aspheric of extended focus
In recent years, peripheral refraction has received increasing attention in research on myopia, based on the theory (demonstrated in animals2) that a hyperopic defocus on the peripheral retina can promote the onset or the progression of myopia3,4. It has been clinically demonstrated that specific multifocal contact lens designs are capable of reducing the progression of myopia in children and young people, if they are capable of inducing relative myopia in the peripheral zone of the retina5-7. One of these designs is based on the concept of fractal lenses8, whose design is shown in Figure 3. Numerical simulations made in theoretical eyes show that these lenses induce a growing myopic defocus with the eccentricity towards the peripheral retina in the horizontal meridian (Figure 4). Currently, the first tests in real patients of the effect of these lenses are being carried out.
Therefore, the development of fractal lenses, allow us to work at two levels. On the one hand they will help us design models for the control of the evolution of myopia, and on the other hand we can adapt these new ideas to design contact lenses to be useful when it comes to solving the focus problems that appear in presbyopia.
Figure 3. Fractal contact lens. a) Distribution of areas of different power. b) Radial power profile
Figure 4. Peripheral refraction obtained numerically in a model eye (right eye). For the contact lens centered lines continuous and offset laterally 0.7 mm towards the temporary side.
An important issue to consider when talking about the use of contact lenses for the correction of presbyopia is that of stereoscopic vision. We do a disservice, if in using a method of improving visual acuity, we produce a significant alteration of the vision of depth perception that hinders the realization of ordinary life9. There are numerous articles on the subject that, while highlighting that the use of this type of contact lenses slightly affects the stereoscopic vision, it is not a modification that really affects the development of everyday life10. But there are two central points to consider: on one hand the hydration of the contact lens and on the other the position or the centering thereof.
Hydration of the lens is essential not only when establishing the tolerance of the lens, but also to maintain the optical results for which the lens is designed. Many of the optical qualities depend on the constant shape of the lens, and if the hydration is compromised, so will those optical qualities. We want to highlight that the incidence of ocular dryness in patients with presbyopia is as we know much greater than that of non-presbyopic patients. For this reason, we must take into account this parameter.
On the other hand, the centering of the lens will also be essential when it comes to being able to use the designs for near vision, whether they are for central or peripheral vision.
The manipulation of the contact lenses may also be compromised in these patients, which is why we recommend that if we are going to use contact lenses, we should do it more frequently in those patients who have previously worn contact lenses.
Once all the possibilities have been established, as throughout the chapter, we would recommend to:
One of the most important conclusions is that the use of contact lenses requires a careful medical study of the ocular surface as well as other characteristics, related not only to the patient's vision, but also to the substrate in which these contact lenses are to be used and the way they are going to be.
Obviously, the dry eye has to be avoided when considering the use of contact lenses in general and of these in particular, that is the dry eye is even a contraindication in the use of this strategy for the correction of presbyopia. In general, as with other techniques, it is important not to create false expectations for the patient. It is interesting to "offer less" and thus "surprise" pleasantly with the results obtained. Although in any case and after the discussion in this chapter, we can clearly say that well indicated contact lenses, and a customized strategy used in each patient is a good option to correct presbyopia.
We would thus answer the initial question we asked ourselves. Perhaps an important aspect is to offer in turn, the rest of both medical and surgical possibilities that we have, for the correction of presbyopia. The patient should have all the information of the possibilities to be able to make a decision with criteria, and that happens either because we have all these options, or because we explain the options, and know how to refer the patient to centers where they can take them out, since it is very important in the long term that patients are satisfied with their decision and with our attitude.
1. Ehrich W, Heitz R, Ist die "LUCE" im manuskript K (fol, 118 verso) von Leonardo da Vinci ein Kornhautmodell oder gar eine kontaktlinse? Contactology 1988; 10D: 1-3
2. Smith EL, Kee C, Ramamirtham R, Qiao-Grider Y, Hung L. Peripheral vision can influence eye growth and refractive development in infant monkeys. Invest Ophthalmol Vis Sci 2005; 46 (11): 3965-72.
3. Mutti DO, Hayes JR, Mitchell GL, Jones LA, Moeschberger ML, Cotter SA, Kleinstein RN, Manny RE, Twelker JD, Zadnik K, CLEERE Study Group. Refractive error, axial length, and peripheral refractive error before and after the onset of myopia. Invest Ophthalmol Vis Sci 2007; 48 (6): 2510-9.
4. Radhakrishnan H, Allen PM, Calver RI, Theagarayan B, Price H, Rae S, Sailoganathan A, O'Leary DJ. Peripheral refractive changes associated with myopia progression. Invest Ophthalmol Vis Sci 2013; 54 (2): 1573-81.
5. Aller TA, Wildsoet C. Bifocal soft contact lenses as a possible myopia control treatment: a case report involving identical twins. Clin Exp Optom2008; 91 (4): 394-9.
6. Sankaridurg P, Holden B, Smith E 3rd, Naduvilath T, Chen X, from Jara PL, Martinez A, Kwan J, Ho A, Frick K, Ge J. Decrease in rate of myopia progression with a contact lens designed to reduce about peripheral hyperopia: one-year results. Invest Ophthalmol Vis Sci 2011; 52 (13): 9362-7.
7. Anstice NS, Phillips JR. Effect of dual-focus soft contact lens wear on axial myopia progression in children. Ophthalmology 2011; 118: 1152-61.
8. Rodriguez-Vallejo M, Benlloch J, Pons A, Monsoriu JA, Furlan WD. The effect of Fractal Contact Lenses on refraction in myopic model eyes. Curr Eye Res. 2014 Apr 21; 39 (12): 1151-60.
9. Sheedy JE, Harris MG, Bronge MR, Joe SM, Mook MA. Task and visual performance with concentric bifocal contact lenses. Optom Vis Sci 1991; 68: 537-41.
10. Woods J, Woods CA, Fonn D. Early symptomatic presbyopes-what correction modality works best? Eye Contact Lens 2009; 35: 221-6.